DIABETES
WHAT IS DIABETES
Serious, chronic disease that occurs either:
When the pancreas does not produce enough insulin
The body cannot effectively use the insulin it produces
Results in raised blood glucose
May lead to serious damage to the heart, blood vessels, eyes, kidneys and nerves
More than 400 million people currently live with diabetes
TYPES OF DIABETES
Type 1 – Deficient insulin production in the body
Require daily administration of insulin to regulate the amount of glucose in the blood
Without it, they cannot survive
Cause not known
Not preventable
Symptoms excessive urination and thirst, constant hunger, weight loss, vision
changes and fatigue
TYPES OF DIABETES
Type 2 – Results from the bodys ineffective use of insulin
Accounts for the vast majority of people with diabetes globally
Symptoms may be similar to those of type 1 diabetes
Often less marked or absent
As a result, the disease may go undiagnosed for several years, until complications
have already arisen
Previously seen only in adults but now more prevalent in children.
TYPES OF DIABETES
Impaired glucose tolerance and impaired fasting glycaemia
Intermediate conditions between normal blood glucose levels and diabetes (especially type 2)
Transition doesnt always occur
Those with the condition are at increased risk of heart attacks and strokes
Gestational Diabetes
Temporary condition that occurs in pregnancy
Carries long term risk of type 2 diabetes
At increased risk of some complications during pregnancy and delivery, including infants
Diagnosed through prenatal screening
DIABETES RISK FACTORS
Type 1 Unknown causes
Thought to result from a complex interaction between genes and environmental factors
No specific environmental risk factors shown to cause a significant number of cases
Primarily occurs in children and adolescents
Type 2 Caused by interplay of genetic and metabolic factors
Ethnicity, family history of diabetes, and previous gestational diabetes combined with older
age, overweight and obesity, unhealthy diet, physical inactivity and smoking increase risk.
Overweight and obesity together with physical inactivity cause a large proportion of global
diabetes burden
DIABETES RISK FACTORS
Gestational diabetes
Age (the older a woman of reproductive age is, the higher her risk of GD)
Overweight or obesity
Excessive weight gain during pregnancy
Family history of diabetes
GD during a previous pregnancy
History of stillbirth or giving birth to an infant with congenital abnormality;
Excess glucose in urine during pregnancy
CONSEQUENCES
Can damage the heart, blood vessels, eyes, kidneys, and nerves
two three-fold increased risk of heart attacks and strokes in adults
Increased chance for foot ulcers, infection and eventual need for limb
amputation
Diabetic retinopathy can cause blindness
2.6% of global blindness can be attributed to diabetes
Among the leading causes of kidney failure
ECONOMIC IMPACT
Diabetes imposes a on the system
Direct annual cost to the world is more than US$ 827 billion
Expenditures for preventing and treating diabetes and its complications
Outpatient and emergency care; inpatient hospital care; medications and medical supplies; and long-term care
Impact on national economies
Estimated GDP losses worldwide from 2011 to 2030 – US$ 1.7 trillion
US$ 900 billion for high-income countries
US$ 800 billion for low- and middle-income countries
BURDEN
Diabetes currently affects over 425 million people worldwide
Up from 108 million in 1980
The global prevalence among adults has risen from 4.7% in 1980 to 8.5% in 2014
Rising more rapidly in middle- and low-income countries
In 2016, an estimated 1.6 million deaths directly caused by diabetes
Seventh leading cause of death in 2016
Another 2.2 million deaths attributable to high blood glucose during 2012
Almost half of all deaths attributable to high blood glucose occur before the age of 70 years
Estimated prevalence and number of adults aged 18 years and older with diabetes
by WHO Region (2014)
OF ADULTS WITH DIABETES FOR 2014
Trends in diabetes prevalence, 1980 2014, by country income group
PREVENTION
How can prevalence of diabetes be reduced?
Simple lifestyle measures
Prevents or delays type 2 diabetes onset
Achieve and maintain health body weight
Physically active
Healthy diet
Avoid tobacco use
Smoking increases the risk of diabetes
WHO RESPONSE
Provide scientific guidelines for the prevention diabetes
WHO “Global report on diabetes
WHO “Global strategy on diet, physical activity and health
Develop norms and standards for diabetes diagnosis and care for all countries
Build awareness on the global epidemic of diabetes, marking World Diabetes
Day (November 14th)
Conducts surveillance of diabetes and its risk factors
INTERNATIONAL DIABETES FEDERATION (IDF)
Incorporated in 1950
An umbrella organization of over 230 national diabetes associations in 170
countries and territories
Promote diabetes care, prevention and a cure worldwide
Instrumental in shaping the international agenda to reduce diabetes globally
Launched the Dubai Blueprint in 2011
Conceived as a practical tool for future action on diabetes for all sectors